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Clinical Papers

Treatment of photoaging with a dual-wavelength, 532 nm and 1,064 nm picosecond-domain laser using a holographic optic


PubMed Reference: Bernstein E, Schomacker KT, Paranjape AS. J Drugs Dermatol. 2017 Nov 1;16(11):1077-1082. 

Study Details: 

  • 14 subjects (2 males, 12 females) with mild-moderate wrinkles, skin phototypes I-IV and mean age 45 (range 23 to 70) years treated with Resolve 1064nm handpiece
  • 10 female subjects with skin phototypes II-IV and mean age 45 (range 23 to 65) years treated with Resolve 532 nm handpiece
  • 5 treatments with 1064nm & 4 treatments with 532nm
  • 3 blinded physicians reviewed 72 digital clinical images, using a 11-point scale (0=no improvement up to 10=100% improvement)

Study Results: 

  • Blinded assessment correctly identified 72% of the baseline images
  • 86% of subjects treated with 1064nm and 80% of subjects treated with 532nm were satisfied to very satisfied with outcome
  • Mild and transient erythema and edema associated with treatment, resolving within several hours.
  • No hyper- or hypo-pigmentation or scarring