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Clinical Papers

Prospective comparison treatment of 595-nm pulsed-dye lasers for virgin port-wine stain


PubMed Reference: Yu W, Ma G, Qiu Y, Chen H, et al. Br J Dermatol. 2015 Mar.

Study Details: 

  • 22 subjects with PWS treated on adjacent sites by both Vbeam and Cynergy 595nm PDL devices.
  • Vbeam parameters: radiant exposure of 11 J/cm2, 1.5 ms pulse duration, 7 mm spot size, DCD cooling (30 ms cooling/20 ms delay).
  • Cynergy® (Cynosure Corp) parameters: radiant exposure of 11 J/cm2, 2 ms pulse duration, 7 mm spot size, cold-air cooling system of level three.
  • 3 treatments on both sites.
  • Chromameter and visual assessment at 2-months post treatment.

Study Results: 

  • Average blanching rate was statistically higher for Vbeam sites (36.4%) compared to Cynergy sites (21.24%).
  • No scarring or permanent pigmentation change.