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Clinical Papers

Evaluation of the Safety and Efficacy of the Dual Wavelength Picosecond Laser for the Treatment of Benign Pigmented Lesions in Asians


PubMed Reference: Kung KY, Shek SY, Yeung CK, Chan HH. Lasers Surg Med. 2019 Jan;51:14-22.

Study Details: 

  • 12 female subjects (mean age 47.3 years, range 37-57; Fitzpatrick skin types III to IV) with benign pigmentary disorders
  • PicoWay 532nm and 1064nm treatments at 2 to 6-week intervals
  • Blinded evaluation of % clearance using clinical photography
  • Follow-ups at 4, 8, and 12 weeks after the last treatment session

Study Results: 

  • Over 90% of all pigments achieved good or excellent response (>50% lightening) at both 1-month and 2-month follow-ups
  • Clinical improvement was better for freckles and lentigines than melasma
  • Lower rate of PIH induced by picosecond laser is explained by a much more targeted photomechanical and lesser photothermal effects than Q-switched laser