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Clinical Papers

Clinical experience in skin rejuvenation treatment in Asians using a long-pulse Nd:YAG laser


PubMed Reference: Chiba C, Usui A, Hara H, Ishi Y. J Cosmet Laser Ther. 2009 Sep.

Study Details:

  • 19 female Japanese patients (Fitzpatrick skin types III or IV) with wrinkles, skin texture, and skin laxity
  • 2 to 7 long-pulse Nd:YAG laser (GentleYAG) treatments every 3-4 weeks
  • 8-mm spot size, pulse duration of 0.3 msec, fluence of 13 J/cm2, repetition rate of 7Hz, and no cryogen spray cooling, using a constant, painting motion technique
  • 3 blinded dermatologists evaluated degree of improvement on a 5-point scale
  • Histological findings in 1 patient.

Study Results:

  • 53% of the patients experienced either good or excellent (>50%) improvement
  • Increase in density of collagen fibers at the treated sites in the papillary dermis 
  • No adverse effects such as purpura, hyperpigmentation, blistering or scarring.