PubMed Reference: Chiba C, Usui A, Hara H, Ishi Y. J Cosmet Laser Ther. 2009 Sep.
- 19 female Japanese patients (Fitzpatrick skin types III or IV) with wrinkles, skin texture, and skin laxity
- 2 to 7 long-pulse Nd:YAG laser (GentleYAG) treatments every 3-4 weeks
- 8-mm spot size, pulse duration of 0.3 msec, fluence of 13 J/cm2, repetition rate of 7Hz, and no cryogen spray cooling, using a constant, painting motion technique
- 3 blinded dermatologists evaluated degree of improvement on a 5-point scale
- Histological findings in 1 patient.
- 53% of the patients experienced either good or excellent (>50%) improvement
- Increase in density of collagen fibers at the treated sites in the papillary dermis
- No adverse effects such as purpura, hyperpigmentation, blistering or scarring.